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Case Report
Bronchial compression in an infant with isolated secundum atrial septal defect associated with severe pulmonary arterial hypertension
Sung-Hee Park, So Young Park, Nam Kyun Kim, Su-Jin Park, Han Ki Park, Young Hwan Park, Jae Young Choi
Clin Exp Pediatr. 2012;55(8):297-300.   Published online August 23, 2012

Symptomatic pulmonary arterial hypertension (PAH) in patients with isolated atrial septal defect (ASD) is rare during infancy. We report a case of isolated ASD with severe PAH in an infant who developed airway obstruction as cardiomegaly progressed. The patient presented with recurrent severe respiratory insufficiency and failure to thrive before the repair of the ASD. Echocardiography confirmed volume overload on...

Original Article
Tumor Necrosis Factor and Lymphotoxin-α Gene Polymorphism in Korean Children with Type 1 Diabetes
Jin Soon Suh, So Young Park, Min Ho Jung, Byung Kyu Suh, Tae Gyu Kim, Byung Churl Lee
Clin Exp Pediatr. 2005;48(8):871-876.   Published online August 15, 2005
Purpose : Recently, it was reported that tumor necrosis factor(TNF) and lymphotoxin-α(LT-α) gene regions might be a susceptible loci to type 1 diabetes in Japanese. The purpose of this study was to investigate the association of TNF and LT-α gene polymorphisms with disease susceptibility in Korean children with type 1 diabetes. Methods : Forty-nine Korean children with type 1 diabetes(29...
Construction and Application of Painting probe for Chromosome band 5q14-q15, 6q23, 16p11.2 and 22q12
Soo-Yeun Park, So Young Park, Joon-Il Kil, Yong-Hyuck Chun, Sun-Hwa Park
Clin Exp Pediatr. 2000;43(2):179-187.   Published online February 15, 2000
Purpose : Chromosome microdissection has become a very powerful approach to generate chromosome band-specific library and painting probes for physical mapping or cytogenetic analysis. We have constructed here band-specific painting probes for human chromosomes by microdissection and polymerase chain reaction(PCR). Methods : We pretreated the microdissected fragments with Topoisomerase I(Topo I) which catalyzes the relaxation of supercoiled DNA, and performed...
Case Report
A Case of Myositis Ossificans Progressiva
So Young Park, Su Jin Lee, Ji A Chung, Seung Joo Lee
Clin Exp Pediatr. 1998;41(11):1601-1605.   Published online November 15, 1998
Myositis ossificans progressiva(MOP) is a rare, slow progressive autosomal dominant disorder that principally affects children under the age 10 years. It is characterized by progressive fibroblastic proliferation, and subsequent calcification and ossification of subcutaneous fat, muscles, tendons, aponeuroses and ligaments. The disorder is often associated with symmetrical malformations of the digits, especially microdactyly or adactyly of the thumbs and great...
Original Article
The Clinical Significance of Serum Sodium Concentration in Febrile Convulsion
So Young Park, Seung Joo Lee
Clin Exp Pediatr. 1998;41(9):1262-1267.   Published online September 15, 1998
Purpose : Recently hyponatremia was reported to be common in febrile convulsion and related to the probability of a repeated convulsion. It was documented that hyponatremia lowers the threshold for convulsion in experiment animals. We therefore studied the relationship between hyponatremia and febrile convulsion. Methods : Serum sodium concentration was measured in 82 children with febrile convulsions and 66 age-matched febrile...
The Diagnostic Value of CSF Tumor Necrosis Factor-α for Early Diagnosis of Bacterial Meningitis
So Young Park, Soo Ja Hwang, Eun Ae Park, Jung Wan Seo, Seung Joo Lee
Clin Exp Pediatr. 1998;41(8):1078-1083.   Published online August 15, 1998
Purpose : During the course of bacterial meningitis, TNF-α produced by macrophages and monocytes in response to LPS and other inflammatory and immune stimulation, is now recognized as a primary mediator in the pathogenesis of infection, injury and inflammation and in the process of host defence. TNF-α was increased vascular permeability by inducing morphologic and structural changes of endothelial cells...
Random Urine Ca/Cr Ratio in Healthy Neonates
Hea Young Lee, So Young Park, Eun Sun Yoo, Eun Ae Park, Seung Joo Lee
Clin Exp Pediatr. 1998;41(3):378-382.   Published online March 15, 1998
Purpose : Recently, in high risk preterm infants, we experienced high incidence of hypercalciuria, nephrolithiasis & nephrocalcinosis. To screen hypercalciuria, we need the normal value of random urine Ca/Cr ratio in healthy neonates according to gestational age, postnatal age, milk and calcium intake. Methods : Random urine Ca/Cr ratio was checked in 260 healthy full-term infants at the 2-7th day, and...
Pulmonary Function Test in Korean Neonates by Expiratory Flow-Volume Curve
So Young Park, Kyung Hyo Kim, Gyoung Hee Kim
Clin Exp Pediatr. 1996;39(1):53-62.   Published online January 15, 1996
Purpose : Neonatal pulmonary function test(PFT) adds a new dimension to the understanding and care of the infant at risk for lung dysfunction. PFT can be identified the risk for pulmonary problems and safely and effectively diagnosed, quantified, and qualified the dysfunction. So it is possible to early institution of prophylatic respiratory therapy in such neonates and it can improved...
Case Report
A Case of Eosinophilic Cystitis in Child
So Young Park, Seung Joo Lee
Clin Exp Pediatr. 1995;38(8):1155-1159.   Published online August 15, 1995
Since Brown first descirbed the eosinophilic granuloma in 1960, 45 cases of eosinophilic cystitis have been reported in the literature, including 10 pediatric cases. In Korea, only four adult cases were reported. Eosinophilic cystitis is characterized by severe infiltration o eosinophils into the mucosa, submucosa and muscularis of bladder wall which causes irritative voiding symptoms. This lesions have been frequently...
A Case of Sturge-Weber Syndrome.
Soo Young Kim, Hyang Sook Kim, Myung Sook Kim, So Young Park, Dong Hak Shin
Clin Exp Pediatr. 1981;24(11):1111-1115.   Published online November 15, 1981
Recently, we experienced a case of Sturge-Weber Syndrome in a 9 month old female. The diagnosis was established by typical clinical features of Sturge-Weber Syndrome in eluding facial portwine nevus, convulsion, left hemiparesis, glaucoma and typical calcification & brain atrophy as seen on on the brain CAT. Plain radiolographys of the skull revealed no evidence of calcification, while the brain...
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